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Pereira L, Levran O, Ramirez F et al. A molecular approach to the stratification of cardiovascular risk in families with Marfan’s syndrome. N Engl J Med 1994;331:148-53.

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2001-2009

McClung MR, Geusen P, Miller PD et al. Effect of risendronate on the risk of hip fracture in elderly women. N Engl J Med 2001;344:333-40.

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Smith MR, McGovern FJ, Zietman AL et al. Pamidronate to prevent bone loss during androgen deprivation therapy for prostate cancer. N Engl J Med 2001;345:948-55.

White MP, Obrecht SE, Finnegan PM et al. Osteoprotegerin deficiency and Juvenile Paget’s Disease. N Engl J Med 2002;347:175-84.

Boyden LM, Mao J, Belsky J et al. High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med 2002;346:1513-21.

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Jonsson KB, Zahradnik R, Larsson T et al. Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia. N Engl J Med 2003;348:1656-63.

Wooley DE. The mast cells in inflammatory arthritis. N Engl J Med 2003;348:1709-11.

Hudson BG, Tryggvason K, Sundaramoorthy M et al. Alport’s syndrome, Goodpasture’s syndrome, and type IV collagen. N Engl J Med 2003;348:2543-56.

Ahlborg HG, Johnell O, Turner CH et al. Bone loss and bone size after menopause. N Engl J Med 2003;349:327-334.

Seeman E. Periosteal bone formation. A neglected determinant of bone strength. N Engl J Med 2003;349:320-3.

Whyte MP, Wenkert D, Clements KL et al. Bisphosphonate-induced osteopetrosis. N Engl J Med 2003;349:457-63.

Black DM, Greenspan SL, Ensrud KE et al. The effect of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med 2003;349:1207-15.

Khosla S. Parathyroid hormone plus alendronate. A combination that does not add up. N Engl J Med 2003;349:1277-9.

Finkelstein JS, Hayes A, Hunzelman JL et al. The effect of parathyroid hormone, alendronate or both in men with osteoporosis. N Engl J Med 2003;349:1216-26.

Tian E, Zhan F, Walker R et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 2003;349:2483-94.

Shattuck TM, Valimaki S, Obara T et al. Somatic and germline mutations of the HRPT2 gene in sporadic parathyroid carcinoma. N Engl J Med 2003;349:1722-9.

Meunier PJ, Roux C, Seeman E et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004;350:459-68.

Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. N Engl J Med 2004;350:482-92.

El-Hajj Fuleihan G. Strontium ranelate – A novel therapy for osteoporosis or a permutation of the same ? N Engl J Med 2004;350:504-6.

Shane E, Adesso V, Namerow PB et al. Alendronate versus calcitriol for the prevention of bone loss after cardiac transplantation. N Engl J Med 2004;350:767-76.

Strewler GJ. Decimal point – Osteoporosis therapy at the 10-year mark. N Engl J Med 2004;350:1172-4.

Bone HG, Hosking D, Devogelaer JP et al. Ten years’ experience with alendronate for osteoporosis in postmenopausal women. N Engl J Med 2004;350:1189-99.

Block GA, Martin KJ, de Francisco ALM et al. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. N Engl J Med 2004;350:1516-25.

Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;350:1655-64.

van Meurs JBJ, Dhonukshe-Rutten RAM, Pluijm SMF et al. Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med 2004;350:2033-41.

Mclean RR, Jacques PF, Selhub J et al. Homocysteine as a predictive factor for hip fracture in older person. N Engl J Med 2004;350:2042-9.

Raisz LG. Homocysteine and osteoporotic fracture –culprit or bystander ? N Engl J Med 2004;350:2089-90.

Welt CK, Chan JL, Bullen J et al. Recombinant human leptin in women with hypothalamic amenorrhea. N Engl J Med 2004;351:987-91.

Zimmerli W, Trampuz A, Ochsner PE. Prostetic-joint infections. N Engl J Med 2004;351:1645-54.

Tolar J, Teitelbaum SL, Orchard PJ. Osteopetrosis. N Engl J Med 2004;351:2839-49.

Shahinian VB, Kuo Y-F, Freeman JL et al. Risk of fracture after androgen deprivation for prostate cancer. N Engl J Med 2005;352:154-64.

Steward AF. Hypercalcemia associated with cancer. N Engl J Med 2005;352:373-9.

Silverman E, Mouy R, Spiegel L et al. Leflunomide or methotrexate for juvenile Rheumatoid Arthritis. N Engl J Med 2005;352:1655-66.

Liu Y-F, Chen W-M, Lin Y-F et al. Type II collagen gene variants and inherited osteonecrosis of the femoral head. N Engl J Med 2005;352:2294-2301.

Eghbali-Fatourechi GZ, Lamsam J, Frase D et al. Circulating osteoblast-lineage cell in humans. N Engl J Med 2005;352:1959-66.

Canalis E. The fate of circulating osteoblasts. N Engl J Med 2005;352:2014-6.

Maerevoet M, Martin C, Duck L. Osteonecrosis ofthe jaw and bisphosphonates. N Engl J Med 2005;353:99-102.

Raisz LG. Screening for osteoporosis. N Engl J Med 2005;353:164-71.

Karsenty G. An aggrecanase and osteoarthritis. N Engl J Med 2005;353:522-3.

Black DM, Bilezikian JP, Ensrud KE et al. One year of alendronate after one year of parathyroid hormone (1-84) for osteoporosis. N Engl J Med 2005;353:555-65.

Cosman F, Nieves J, Zion M et al. Daily and cyclic parathyroid hormone in women receiving alendronate. N Engl J Med 2005;353:566-75.

Heaney RP, Recker RR. Combination and sequential therapy for osteoporosis. N Engl J Med 2005;353:624-5.

Cundy T, Davidson J, Rutland MD et al. Recombinant osteoprotegerin for Juvenile Paget’s Disease. N Engl J Med 2005;353:918-23.

Somerville MJ, Mervis CB, Young EJ et al. Severe expressive-language delay related to duplication of the William-Beuren locus. N Engl J Med 2005;353:1694-1701.

Rhen T, Cidlowski JA. Antinflammatory action of glucocorticoids – new mechanisms for old drugs. N Engl J Med 2005;353:1711-23.

Kaplan MM, Gershwin ME. Primary biliary cirrhosis. N Engl J Med 2005;353:1261-73.

Petri M, Kim MY, Kalunian KC et al. Combined oral contraceptive in women with systemic lupus erythematosus. N Engl J Med 2005;353:2550-8.

Firestein GS. Inhibiting inflammation in Rheumatoid Arthritis. N Engl J Med 2006;354:80-2.

Jackson RD, LaCroix AZ, Gass M et al. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med 2006;354:669-83.

Finkelstein JS. Calcium plus vitamin D for postmenopausal women – bone appetit ? N Engl J Med 2006;354:750-2.

McClung MR, Lewiecki EM, Cohen SB et al. Denosumab in postmenopausal women with low bone mineral density. N Engl J Med 2006;354:821-31.

Tryggvason K, Patrakka J, Wartiovaara J. Hereditary proteinuria syndromes and mechanisms of proteinuria. N Engl J Med 2006;354:1387-1401.

Berman E, Nicolaides M, Maki RG et al. Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med 2006;354:2006-13.

Seeman E, Delmas PD. Bone quality – the material and structural basis of bone strength and fragility. N Engl J Med 2006;354:2250-8.

Whyte MP. Paget’s disease of bone. N Engl J Med 2006;355:593-600.

Drenth JPH, van der Meer JWM. The inflammasome – a linebacker of innate defense. N Engl J Med 2006;355:730-2.

Goldback-Masky R, Dailey NJ, Canna SW et al. Neonatal onset multisystem inflammatory disease responsive to interleukin-1 beta inhibition. N Engl J Med 2006;355:581-92.

Loeys BL, Schwarze U, Holm T et al. Aneurysm syndromes caused by mutations in the TGFbeta receptor. N Engl J Med 2006;355:788-98.

Gelb BD. Marfan’s syndrome and related disorders – more tightly connected than we thought. N Engl J Med 2006;355:841-48.

Nair KS, Rizza RA, O’Brien P et al. DHEA in elderly women and DHA and Testosterone in elderly men. N Engl J Med 2006;355:1647-59.

Bilezikian JP. Osteonecrosis of the jaw – do bisphosphonates pose a risk ? N Engl J Med 2006;355:2278-81.

Barnes AM, Chang W, Morello R et al. Deficiency of cartilage-associated protein in recessive lethal Osteogenesis Imperfecta. N Engl J Med 2006;355:2757-64.

Huttenlocher A, Horwitz AR. Wound healing with electric potential. N Engl J Med 2007;356:303-4.

Tonetti MS, D’Aiuto F, Nibali L et al. Treatment of periodontitis and endothelial function. N Engl J Med 2007;356:911-20.

Jin Y, Mailloux CM, Gowan K et al. NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med 2007;356:1216-25.

Black DM, Delmas PD, Eastell R et al. Once-yearly Zolendronic acid for treatment of postmenopausal osteoporosis. N Engl J Med 2007;356:1809-22.

Weinstein JN, Tosteson TD, Lurie JD et al. Surgical versus non surgical therapy for lumbar spinal stenosis. N Engl J Med 2007;356:794-810.

Weinstein JN, Lurie JD, Tosteson TD et al. Surgical versus non surgical treatment for lumbar degenerative spondylolisthesis. N Engl J Med 2007;356:2257-70.

Peul WC, von Houwelingen HC, van der Haut WB et al. Surgery versus prolonged conservative treatment for sciatica. N Engl J Med 2007;356:2245-56.

Deyo RA. Back surgery. Who need it ? N Engl J Med 2007;356:2239-43.

Khosla S, Melton LJ III. Osteopenia. N Engl J Med 2007;356:2293-2300.

Lipsky PE. Why does rheumatoid arthritis involve the joints ? N Engl J Med 2007;356:2419-20.

Haas D, Hoffmann GF. Mevalonate kinase deficiency and autoinflammatory disorders. N Engl J Med 2007;356:2671-3.

Neven B, Valayannopoulos V, Quartier P et al. Allogenic bone marrow transplantation in mevalonic aciduria. N Engl J Med 2007;356:2700-3.

Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81.

Canalis E, Giustina A, Bilezikian JP. Mechanism of anabolic therapies for osteoporosis. N Engl J Med 2007;357:905-16.

Plenge RM, Seielstad M, Padyukov L et al. TRAF1-C5 as a risk locus for Rheumathoid Arthritis – A genomewide study. N Engl J Med 2007;357:1199-1209.

Remmers EF, Plenge RM, Lee AT et al. STAT4 and the risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus. N Engl J Med 2007;357:977-86.

Calis KA, Pucino F. Zolendronic acid and secondary prevention of fractures. N Engl J Med 2007;357:1861-2.

Saag KG, Shane E, Boonen S et al. Teriparatide or alendronate in glucocorticoid induced osteoporosis. N Engl J Med 2007;357:2028-39.

Allen KJ, Gurrin LC, Constantine CC et al. Iron-overload related disease in HFE hereditary hemochromatosis. N Engl J Med 2008;358:221-30.

Sarelli AE, Janssen WJ, Sterman D et al. What’s the connection ? N Engl J Med 2008;358:626-32. ( Clinical Problem Solving on Ehlers-Danlos syndrome of vascular type ).

Hom G, Graham RR, Modrek B et al. Association of Systemic Lupus Erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 2008;358:900-9.

Rahman A, Isenberg DA. Systemic Lupus Erythematosus. N Engl J Med 2008;358:929-39.

Lenart BA, Lorich DG, Lane JM. Atypical fractures of the femoral diaphysis in postmenopausal women taking alendronate. N Engl J Med 2008;358:1304-6.

Matsen FA III. Rotator-cuff failure. N Engl J Med 2008;358:2138-47.

Styrkarsdottir U, Halldorsson BV, Gretarsdottir S et al. Multiple genetic loci for bone mineral density and fractures. N Engl J Med 2008;358:2355-65.

Ebeling PR. Osteoporosis in men. N Engl J Med 2008;358:1474-82.

Brooke BS, Habashi JP, Judge DP et al. Angiotensin II blockade and aortic root dilatation in Marfan’s syndrome. N Engl J Med 2008;358:2787-95.

Peyritz RE. A small molecule for a large disease. N Engl J Med 2008;358:2829-31.

Shoback D. Hypoparathyroidism. N Engl J Med 2008;359:391-403.

Gutierrez OM, Mannstadt M, Isakova T et al. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med 2008;359:584-92.

Hsu C. FGF-23 and outcomes research – when physiology meets epidemiology. N Engl J Med 2008;359:640-1.

Karim Z, Gerard B, Bakouh N et al. NHERF1 mutations and responsiveness of renal parathyroid hormone. N Engl J Med 2008;359:1128-35.

Mefford H, Sharp A, Baker C et al. Recurrent rearrangements of chromosome 1q21.1and variable pediatric phenotypes. N Engl J Med 2008;359:1658-99.

Davis SR, Moreau M, Kroll R et al. Testosterone for low libido in postmenopausal women not taking estrogen. N Engl J Med 2008;359:2005-17.

Weinstein RS, Roberson PK, Manolagas SC. Giant osteoclast formation and long-term oral bisphosphonate therapy. N Engl J Med 2009;360:53-62.

Bulun SE. Endometriosis. N Engl J Med 2009;360:268-79.

Gnant M, Mlineritsch B, Schippinger W et al. Endocrine therapy plus zolendronic acid in premenopausal breast cancer. N Engl J Med 2009;360:679-91.

Rosen CJ. Serotonin rising – The bone, brain, bowel connection. N Engl J Med 2009;360:957-9.

Laurenco D, Brauner R, Lin L et al. Mutations in NR5A1 associated with ovarian insufficiency. N Engl J Med 2009;360:1200-9.

Leopold SS. Minimally invasive total knee arthroplasty for osteoarthritis. N Engl J Med 2009;360:1749-58.

Gabrielli A, Avvedimento EV, Krieg T. Scleroderma. N Engl J Med 2009;360:1989-2003.

Noordam C, Dhir V, McNelis JC et al. Inactivating PAPSS2 mutations in a patients with premature pubarche. N Engl J Med 2009;360:2310-8.

Harousseau JL, Moreau P. Autologous hematopoietic stem cell transplantation for multiple myeloma. N Engl J Med 2009;360:2645-54.

Buchbinder R, Osborne RH, Ebeling PR et al. A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 2009;361:557-68.

Kallmes DF, Comstock BA, Heagerty PJ et al. A randomzed trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med 2009;361:569-79.

Smith MR, Egerdie B, Toriz NH et al. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N Engl J Med 2009;361:745-55.

Cummings SR, Martin JS, McClung MR et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 2009;361:756-65.

Mardis ER, Ding L, Dooling DJ et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 2009;361:1058-66.

Downing JR. Cancer genome. Continuing progress. N Engl J Med 2009;361:1111-2.

Riches PL, McRorie E, Fraser WD et al. Osteoporosis associated with neutralizing antibodies against osteoprotegerin. N Engl J Med 2009;361:1459-65.

Frulloni L, Lunardi C, Simone R et al. Identification of a novel antibody associated with autoimmune pancreatitis. N Engl J Med 2009;361:2135-42.

2010

Smits P, Bolton AD, Funari V et al. Lethal Dysplasia in mice and humans lacking the Golgin GMAP-210. N Engl J Med 2010;362:206-16.

Barnes AM, Carter EM, Cabral WA et al. Lack of cyclophillin B in Osteogenesis Imperfecta with normal collagen folding. N Engl J Med 2010;362:521-8.

Cummings SR, Ensrud K, Delmas PD et al. Lasofoxifene in postmenopausal women with osteoporosis. N Engl J Med 2010;362:686-96.

Zimmerli W. Vertebral Osteomyelitis. N Engl J Med 2010;362:1022-9.

Magen D, Berger L, Coady MJ et al. A loss of function mutation in NaPiIIa and renal Fanconi’s syndrome. N Engl J Med 2010;362:1102-9.

Black DM, Kelly MP, Genant HK et al. Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur. N Engl J Med 2010;362:1761-71.

Shane E. Evolving data about subtrochanteric fractures and bisphosphonates. N Engl J Med 2010;362:1825-7.

Priè D, Friedlander G. Genetic disorders of renal phosphate transport. N Engl J Med 2010;362:2399-2409.

Wu FCW, Tajar A, Beynon JM et al. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med 2010;363:123-5.

Gordon CM. Functional hypothalamic amenorrhea N Engl J Med 2010;363:365-71.

Wang C, Schmid CH, Rones R et al. A randomized trial of Tai Chi for Fibromyalgia. N Engl J Med 2010;363:743-54.

Lane NE, Schnitzer TJ, Birbara CA et al. Tanezumab for the treatement of pain from osteoarthritis of the knee. N Engl J Med 2010;363:1521-31.

Favus MJ. Bisphosphonates for osteoporosis. N Engl J Med 2010;363:2027-35.

Bashutski JD, Eber RM, Kinney JS et al. Teriparatide and osseous regeneration in the oral cavity. N Engl J Med 2010;363:2396-2405.

2011

Chahal HS, Stals K, Unterlander M et al. AIP mutation in pituitary adenomas in the 18th Century and Today. N Engl J Med 2011;364:43-50.

Caronia LM, Martin C, Welt CK et al. A genetic basis for functional Hypothalamic Amenorrhea. N Engl J Med 2011;364:215-25.

Ensrund KE, Schousboe JT. Vertebral fractures. N Engl J Med 2011;364:1634-42.

Marcocci C, Kahaly GJ, Krasses GE et al. Selenium and the course of mild Graves’ orbitopathy. N Engl J Med 2011;364:1920-31.

Linglart A, Menguy C, Couvineau A et al. Recurrent PRKAR1A mutation in Acrodysostosis with hormone resistance. N Engl J Med 2011;364:2218-26.

Weinstein RS. Glucocorticoid-induced bone disease. N Engl J Med 2011;365:62-70.

Schlingmann KP, Kaufmann M, Weber S et al. Mutations in CYP24A1 and Idiopathic Infantile Hypercalcemia. N Engl J Med 2011;365:410-21.

Pramyothin P, Leung AM, Pearce EN et al. A hidden solution. N Engl J Med 2011;365:2123-7.

2012

Gourlay ML, Fine JP, Preisser JS et al. Bone density testing interval and transition to osteoporosis in old women. N Engl J Med 2012;366:225-33.

Whyte MP, Greenberg CR, Salmon NJ et al. Enzyme replacement therapy in life threading hypophasphatemia. N Engl J Med 2012;366:904-13.

Bischoff-Ferrari HA, Willet WC, Oraiv EJ et al. A pooled analysis of vitamin D dose requirements for fracture prevention. N Engl J Med 2012;367:40-9.

Heaney RP. Vitamin D Baseline status and effective dose. N Engl J Med 2012;367:77-8.

Boonen S, Reginster JY, Kaufman JM et L. Fracture risk and zolendronic acid therapy in men with osteoporosis. N Engl J Med 2012;367:1714-23.

Sandborg C, Mellins ED. A new era in the treatment of systemic juvenile idiopathic arthritis. N Engl J Med 2012;367:2439-40.

Ruperts N, Brunner HI, Querties P et al. Two randomized trials of Canakinumab in systemic juvenile idiopathic arthritis. N Engl J Med 2012;367:2396-2406.

De Benedetti F, Brunner HI, Ruperto N et al. Randomized trial of Tocilizumab in systemic iuvenile idiopathic arthritis. N Engl J Med 2012;367:2385-95.

Prockop DJ. New target for osteoporosis. N Engl J Med 2012;367:2353-4.

2013

Ardaugh GH, Graves SE, Redberg RF. The 510(k) ancestry of a metal-on-metal hip implant. N Engl J Med 2013;368:97-100.

Ralston SH. Paget’s disease of bone. N Engl J Med 2013;368:644-650.

Hresko MT. Idiopathic scoliosis in adolescents. N Engl J Med 2013;368:834-41.

el Barzouhi A, Vleggeert-Lankamp Carmen LAM, Lychlama à Nijheolt GC et al. Magnetic resonance imaging in follow-up assessment of sciatica. N Engl J Med 2013;368:999-1007.

Laine CM, Joeng KS, Campeau PM et al. WNT1 mutations in early onset osteoporosis ans osteogenesis imperfecta. N Engl J Med 2013;368:1809-16.

Quaynor SD, Stradtman EW, Kim HG et al. Delayed puberty and estrogen resistance in a woman with estrogen receptor alfa variant. N Engl J Med 2013;369:164-171.

Bauer DC. Calcium supplements and fracture prevention. N Engl J. Med 2013;369:1537-43.

Power CE, Evans MK, Wenger J et al. Vitamin D-binding protein and Vitamin D status in black Americans and white Americans. N Engl J Med 2013;369:1991-2000.

van Dijk FS, Zillikens MC, Micha D et al. PLS3 mutations in X-linked osteoporosis with fractures. N Engl J Med 2013;369:1529-36.

2014

Peltola H, Pääkkönen M. Acute Osteomyelitis in children. N Engl J Med 2014;370:352-60.

McClung MR, Grauer A, Boonen S et al. Romosumab in postmenopausal women with low bone mineral density. N Engl J Med 2014;370:412-20.

Becker CB. Sclerostin inhibition for osteoporosis – A new approach. N Engl J Med 2014;370:476-7.

Hamnvik OP, Becker CB, Levy BD et al. Wasting Away. N Engl J Med 2014:370:959-66.

Lacro RV, Dietz HC, Sleeper LA et al. Atenolol versus Losartan in children and young adults with Marfan syndrome. N Engl J Med 2014;371:2061-71.

Bowen JM, Connolly HM. Of Marfan syndrome, mice, and medications. N Engl J Med 2014;371:2127-8.

2015

Schilcher J, Koepper V, Aspenberg P. et al. Risk of atypical femur fracture during and after bisphosphonate use. N Engl J Med 2014;371:974-6.

Clemens TL. Vitamin B12 deficiency and bone health. N Engl J Med 2014;371:963-4.

Hunter DJ. Viscosupplementation for osteoarthritis of the knee. N Engl J Med 2015;372:1040-7.

Ropper AH, Zafonte RD. Sciatica. N Engl J Med 2015;372:1240-8.

Siddiqui NS, Altorok N. Diffuse soft tissue calcinosis. N Engl J Med 2015;373:173.

Tavare AN, Marmery H. Band acro-osteolysis. N Engl J Med 2015;373:e6.

Heczey A, Louis C. Osteopetrosis and Erlenmeyer-Flask deformity. N Engl J Med 2015;373:e12.

Skou ST, Roos EM, Laursen MB te al. A randomized trial of total knee replacement. N Engl J Med 2015;373:1597-606.

Katz JN. Parachutes and preferences - A trial of knee replacement. N Engl J Med 2015;373:1700-1.

O’Keefe R.J. Fibrinolysis as a target to enhance fracture healing. N Engl J Med 2015;373:1776-8.

2016

Black DM, Rosen CJ. Postmenopausal osteoporosis. N Engl J Med 2016;374:254-262.

Huston BA, Miller E, Rooper LM ET al. From dancing to debilitated. N Engl J Med 2016;374:470-7.

Gryseleyn R, Maes JM, Ferri J. Osteochemonecrosis after mandible reconstruction. N Engl J Med 2016;374:1097-8.

Nielson CM, Jones KS, Chun RF et al. Role of assay type in determining free 25 hydroxyvitamin D levels in diverse population. N Engl J Med 2016;374:1695-6.

Scadden D.T. Blood and Bone. N Engl J Med 2016;374:1891-3.

Simsek Kiper PO, Saito H, Gori F et al. Cortical-bone fragility - Insights from sFRP4 deficiency in Pyle's Disease. N Engl J Med 2016;374:2553-62.

Taurog JD, Chhabra A, Colbert RA. Ankylosing spondylitis and axial spondyloarthritis. N Engl J Med 2016;374:2563-74.

Choy E, Hornicek FJ, Cheyenne Y-L et al. Case 26-2016: A 28 year old woman with back pain and a lesion in the lumbar spine. N Engl J Med 2016;375:779-88.

Cosman F, Crittenden DB, Adachi JD ET al. Romosozumab treatment in postmenopausal women with osteoporosis. N Engl J Med 2016;375:1532-43.

Rosenthal AK, Ryan LM. Calcium pyrophosphate deposition disease.N Engl J Med 2016;374:2575-84.

Rosen C, Ingelfinger JR. Building better bones with biologics- A new approach to osteoporosis ? N Engl J Med 2016;375:1583-4.

Manson JE, Brannon PM, Rosen CJ et al. Vitamin D deficiency - Is there really a pandemic ? N Engl J Med 2016;375:1817-20.

2017

Ritchlin C.T., Colbert R.A., Gladman D.A. Psoriatic Arthritis. N Engl J Med 2017;376:957-70.

Saag G.S., Petersen J., Brandi M.L, ET al. Romosumab or Alendronate for fracture prevention in women with osteoporosis. N Engl J Med 2017;377:1417-27.

Rosen C.J. Romosumab - Promising or Practice changing ? N Engl J Med 2017;377:1479-80.

Bhandari M, Swiontkowski M. Management of acute hip fracture. N Engl J Med 2017;377:2053-62.

Zeiser R., Blazar B.R. Acute Graft-versus-Host disease - Biologic process, Prevention, and Therapy. N Engl J Med 2017;377:2167-79.

2018

Insogna K.L. Primary Hyperparathyroidism. N Engl J Med 2018;379:1050-9.

Reid I.R., Horne A.M., Mihov B.M. ET al. Fracture prevention with Zoledronate in older women with osteopenia. N Engl J Med 2018;379:2407-16.

Rosen C.J. A not-so-new treatment for old bones. N Engl J Med 2018;379:2465-66.

Buckley L, Humphrey M.B. Glucocorticoid-Induced Osteoporosis. N. Engl J Med 2018;379:2547-56.

2019

Li H-K., Rombach I., Zambellas R. et al. Oral versus intravenous antibiotics for bone and joint infection. N Engl J Med 2019;380:425-36.

Boucher HW. Partial oral therapy for osteomyelitis and endocarditis - It is time ? N Engl J Med 2019;380:487-9.

Gafni R.I, Collins M.T. Hypoparathyroidism. N Engl J Med 2019;380:1738-47.

Deb A. How stem cells turn into bone and fat. N Engl J Med 2019;380:2268-70.

Musahl V., Karlsson J. Anterior cruciate ligament tear. N Engl J Med 2019;380:2341-8.

2020

Willet W.C., Ludwig D.S. Milk and Health. N Engl J Med 2000;382:644-54.